Neural correlates of uncertainty during a spatial decision making task.

We expect that aspects of the hippocampal neuronal activity represent the uncertainty of the animal regarding its spatial context and hence population activity can be manipulated by changing the ambiguity of the environment.

In a series of ongoing 2P Ca2+ imaging experiments with Judit Makara, we use mice trained in virtual reality to run for water reward and analyse their hippocampal neuronal activity for signatures of encoding subjective uncertainty in a given trial.